个人信息:
鲍依群,必赢体育唯一官网生物化学与分子生物学教授、博士生导师。南京农业大学‘高层次引进人才’。中国电镜学会农林专业委员会委员。
Email: baoyiqun@njau.edu.cn
地址:生科楼B2019
一、 学习及工作经历:
2008年至今:南京农业大学必赢体育唯一官网教授,博导
2002-2008年:新加坡分子与细胞生物学研究所动物细胞蛋白运输,博士后
1996-2002年:新加坡国立大学淡马锡生命科学研究所植物细胞生物学,博士
1996-1998年:美国洛克菲勒大学,访问学者 (博士期间)
1994-1996年:荷兰瓦赫宁根农业大学植物生物技术,硕士
1986-1990年:南京农业大学食品工程专业,学士
教学情况:
主讲本科生‘细胞生物学’,‘细胞生物学实验’课程。
主讲研究生‘细胞生物学’全英文课程。
三、目前研究方向:
蛋白运输与植物生长发育之间的关系。
水稻农艺性状相关基因的克隆及功能研究。
研究生招生专业:生物化学与分子生物学、细胞生物学
欢迎有志于植物细胞生物学和水稻品质改良研究的青年学子报考(或免试推荐)本人的硕士及博士研究生。
二、目前的课题:
1. 项目名称:南京农业大学引进人才启动基金
2009-2012, 项目主持人
2. 项目名称:Exocyst在花粉管生长中的功能研究
国家自然科学基金(项目编号30970272),2010-2012年,项目主持人
3. 项目名称:四个水稻谷蛋白57H突变体的基因克隆、功能验证和育种利用
转基因生物新品种培育重大专项(项目编号2009zx08009-114B),2009-2010年,项目主持人
4. 项目名称:Exocyst及其互作蛋白在花粉管及胞质分离中的作用
高等学校博士学科点专项科研基金, 博导类(项目编号B0201100672),2012-2014,项目主持人
5. 项目名称:水稻谷蛋白运输储藏关键基因的克隆和功能鉴定
转基因生物新品种培育重大专项(项目编号2014zx08009-025B),2014-2016年,项目主持人
6. 项目名称:植物感受和应答非生物胁迫信号网络的解析与调控
高校基本业务费重点项目(项目编号KYTZ201402),2014-2016,课题负责人
7. 项目名称:拟南芥基于COG复合体的高尔基体形态维持和囊泡运输的分子网络解析
国家自然科学基金(项目编号31770202),2018-2021年,项目主持人
8. 项目名称:水稻谷蛋白合成、运输途径关键基因的发掘和育种利用
转基因生物新品种培育重大专项(项目编号2018zx08009-020B),2018-2019,项目主持人
9.项目名称:CCP1在高尔基体形态维持和花粉管生长中的功能研究
国家自然科学基金(项目编号32070190),2021-2024年,项目主持人
10. 科技部国家重点研发计划“农业生物重要性状形成与环境适应性基础研究”重点专项, 农作物育性与生殖发育分子调控机制(2022YFF1003500),2022-2027,任务负责人
11. 项目名称:Sec11和SEC13蛋白协同GEM1/MOR1调控小孢子不对称分裂中细胞板放置的机理研究
国家自然科学基金(项目编号32370356),2024-2027年,项目主持人
二、 杂志编委:
Plant Science, advisory board member, 2013年-至今
Plant cell biology section of Frontiers in plant science, review editor, 2020年-至今
四、近年发表文章:(* Corresponding author)
1. J. Wu, X. Tan, C. Wu, K. Cao, Y. Li, Y. Bao* (2013) Regulation of Cytokinesis by Exocyst Subunit SEC6 and KEULE in Arabidopsis thaliana, Mol Plant, 6: 1863-1876.
2. F. Liu, Y. Ren, Y. Wang, C. Peng, K. Zhou, J. Lv, X. Guo, X. Zhang, M. Zhong, S. Zhao, L. Jiang, H. Wang, Y. Bao*, J. Wan* (2013) OsVPS9A Functions Cooperatively with OsRAB5A to Regulate Post-Golgi Dense Vesicle-Mediated Storage Protein Trafficking to the Protein Storage Vacuole in Rice Endosperm Cells, Mol Plant, 6:1918-1932.
3. Z. Feng, X. Chen, Y. Bao, J. Dong, Z. Zhang, X. Tao (2013) Nucleocapsid of Tomato spotted wilt tospovirus forms mobile particles that traffic on an actin/endoplasmic reticulum network driven by myosin XI-K, New Phytol, 200: 1212-1224.
4. Y. Ding, J. Wang, J.H. Chun Lai, V.H. Ling Chan, X. Wang, Y. Cai, X. Tan, Y. Bao, J. Xia, D.G. Robinson, L. Jiang (2014) Exo70E2 is essential for exocyst subunit recruitment and EXPO formation in both plants and animals, Mol Biol Cell, 25: 412-426.
5. Y. Ren, Y. Wang, F. Liu, K. Zhou, Y. Ding, F. Zhou, K. Liu, L. Gan, W. Ma, X. Han, X. Zhang, X. Guo, F. Wu, Z. Cheng, J. Wang, C. Lei, Q. Lin, L. Jiang, C. Wu, Y. Bao, H. Wang, J. Wan (2014) GLUTELIN PRECURSOR ACCUMULATION3 Encodes a Regulator of Post-Golgi Vesicular Traffic Essential for Vacuolar Protein Sorting in Rice Endosperm, Plant Cell, 26: 410-425.
6. C. Peng, Y. Wang, F. Liu, Y. Ren, K. Zhou, J. Lv, M. Zheng, S. Zhao, L. Zhang, C. Wang, L. Jiang, X. Zhang, X. Guo, Y. Bao, J. Wan (2014) FLOURY ENDOSPERM6 encodes a CBM48 domain-containing protein involved in compound granule formation and starch synthesis in rice endosperm, Plant J, 77: 917-930.
7. Chen, Y., Chen, X., Wang, H., Bao, Y., and Zhang, W. (2014) Examination of the leaf proteome during flooding stress and the induction of programmed cell death in maize. Proteome science 12, 33.
8. J. Ma, Z. Cheng, J. Chen, J. Shen, B. Zhang, Y. Ren, Y. Ding, Y. Zhou, H. Zhang, K. Zhou, J.L. Wang, C. Lei, X. Zhang, X. Guo, H. Gao, Y. Bao, J.M. Wan (2016) Phosphatidylserine Synthase Controls Cell Elongation Especially in the Uppermost Internode in Rice by Regulation of Exocytosis, PLoS One, 11: e0153119.
9. L. Zhang, Y. Ren, B. Lu, C. Yang, Z. Feng, Z. Liu, J. Chen, W. Ma, Y. Wang, X. Yu, Y. Wang, W. Zhang, Y. Wang, S. Liu, F. Wu, X. Zhang, X. Guo, Y. Bao, L. Jiang, J. Wan (2016) FLOURY ENDOSPERM7 encodes a regulator of starch synthesis and amyloplast development essential for peripheral endosperm development in rice, J Exp Bot, 67: 633-647.
10. X. Tan, Y. Feng, Y. Liu, Y. Bao* (2016) Mutations in exocyst complex subunit SEC6 gene impaired polar auxin transport and PIN protein recycling in Arabidopsis primary root, Plant Science, 250: 97-104.
11. X. Tan, K. Cao, F. Liu, Y. Li, P. Li, C. Gao, Y. Ding, Z. Lan, Z. Shi, Q. Rui, Y. Feng, Y. Liu, Y. Zhao, C. Wu, Q. Zhang, Y. Li, L. Jiang, and Y. Bao* (2016) Arabidopsis COG complex subunits COG3 and COG8 modulate Golgi morphology, vesicle trafficking homeostasis and are essential for pollen tube growth, Plos Genet. 12: e1006140
12. Wang, Y., Liu, F., Ren, Y., Wang, Y., Liu, X., Long, W., Wang, D., Zhu, J., Zhu, X., Jing, R., Wu, M., Hao, Y., Jiang, L., Wang, C., Wang, H., Bao, Y., and Wan, J. (2016) GOLGI TRANSPORT 1B Regulates Protein Export from the Endoplasmic Reticulum in Rice Endosperm Cells. Plant Cell 28, 2850-2865.
13. Sheng, P., Wu, F., Tan, J., Zhang, H., Ma, W., Chen, L., Wang, J., Wang, J., Zhu, S., Guo, X., Wang, J., Zhang, X., Cheng, Z., Bao, Y., Wu, C., Liu, X., and Wan, J. (2016) A CONSTANS-like transcriptional activator, OsCOL13, functions as a negative regulator of flowering downstream of OsphyB and upstream of Ehd1 in rice. Plant Mol Biol 92, 209-222.
14. Li, Y., Tan, X., Wang, M., Li, B., Zhao, Y., Wu, C., Rui, Q., Wang, J., Liu, Z., and Bao, Y.* (2017) Exocyst subunit SEC3A marks the germination site and is essential for pollen germination in Arabidopsis thaliana. Scientific reports 7, 40279.
15. Tan X, Wei J, Li B, Wang M, Bao Y* (2017) AtVps11 is essential for vacuole biogenesis in embryo and participates in pollen tube growth in Arabidopsis. Biochem Biophys Res Commun 491, 794-799.
16. Wu C, Tan L, van Hooren M, Tan X, Liu F, Li Y, Zhao Y, Li B, Rui Q, Munnik T, Bao Y* (2017) Arabidopsis EXO70A1 recruits Patellin3 to the cell membrane independent of its role as exocyst subunit. J Integr Plant Biol 59, 81-865.
17. Li B, Li Y, Liu F, Tan X, Rui Q, Tong Y, Qiao L, Gao R, Li G, Shi R, Li Y, Bao Y* (2019) Overexpressed Tomosyn binds syntaxins and blocks secretion during pollen development. Plant Physiol 181, 1114-1126.
[同期配发评论:Larson ER (2019) Plant Tomosyn is a negative regulator of SNARE-mediated secretion in pollen. Plant Physiol 181, 843-844]
18. Rui Q, Wang J, Li Y, Tan X, Bao Y* (2020) Arabidopsis COG6 is essential for pollen tube growth and Golgi structure maintenance. Biochem Biophys Res Commun 528: 447-452
19. Rui Q, Tan X, Liu F, Li Y, Liu X, Li B, Wang J, Yang H, Qiao L, Li T, Fang S, Gao R, Wang W, Bednarek SY, Bao Y* (2021) Syntaxin of plants31 (SYP31) and SYP32 are essential for Golgi morphology maintenance and pollen development. Plant Physiol 186: 330-343.
[同期配发评论:Dell'Aglio E (2021) A COG in the machine: how good Golgi makes good pollen.
Plant Physiol 186: 201-203]
20. Zhu, J., Ren, Y., Zhang, Y., Yang, J., Duan, E., Wang, Y., Liu, F., Wu, M., Pan, T., Wang, Y., Hu, T., Hao, Y., Teng, X., Zhu, X., Lei, J., Jing, R., Yu, Y., Sun, Y., Bao, X., Bao, Y., Wang, Y., Wan, J. (2021) Subunit E isoform 1 of vacuolar H+-ATPase OsVHA enables post-Golgi trafficking of rice seed storage proteins. Plant Physiol 187: 2192-2208.
21. Cai, Y., Zhang, W., Fu, Y., Shan, Z., Xu, J., Wang, P., Kong, F., Jin, J., Yan, H., Ge, X., Wang, Y., You, X., Chen, J., Li, X., Chen, W., Chen, X., Ma, J., Tang, X., Zhang, J., Bao, Y., Jiang, L., Wang, H., Wan, J. (2022) Du13 encodes a C2 H2 zinc-finger protein that regulates Wx(b) pre-mRNA splicing and microRNA biogenesis in rice endosperm. Plant Biotechnol J 20: 1387-1401.
22. Ren, Y., Wang, Y., Zhang, Y., Pan, T., Duan, E., Bao, X., Zhu, J., Teng, X., Zhang, P., Gu, C., Dong, H., Wang, F., Wang, Y., Bao, Y., Wang, Y., Wan, J. (2022) Endomembrane-mediated storage protein trafficking in plants: Golgi-dependent or Golgi-independent? (DOI: 10.1002/1873-3468.14374)
23. Tan, X., Xu, H., Ye, J., Wang, J., Liu, W., Liu, F., Rui, Q., Bao, Y.* (2022) Arabidopsis exocyst subunit SEC6 is involved in cell plate formation during Microgametogenesis. Biochem Biophys Res Commun 598: 100-106.
24. Rui, Q. Tan, X. Liu, F. Bao, Y.* (2022) An update on the key factors required for plant Golgi structure maintenance. Front Plant Sci 13: 933283.
25. Yang H, Liu F, Wang W, Rui Q, Li G, Tan X, Ye J, Shen H, Liu Y, Liu W, Tang R, Hu J, Liu K, Zhang Y, Zhan H, Wang Y, Bao Y.* (2023) Sporopollenin biosynthesis in an OsTKPR2-containg metabolon is required for rice pollen exine formation. J Exp Bot. doi:10.1093/jxb/erad016
26. Liu F, Yang H, Tang R, Wang W, Shen H, Xu M, Hao T, Hu Y, Zhang Y, Bao Y (2023) OsTKPR1 proteins with a single amino acid substitution fail the synthesis of a specific sporopollenin precursor and cause abnormal exine and pollen development in rice. Plant Sci 335:111792. doi:10.1016/j.plantsci.2023.111792